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Monday, March 5, 2012
New Orleans case puts scrutiny on NFL bounty pay (AP)
Inhabitat's Week in Green: i-oniq hybrid, spherical solar cell and a incredible LEGO printer
It was also a bright week for renewable energy with a revolutionary spherical solar cell capable of capturing light from all directions, and Austria Solar sending out a "sun-powered" annual report that only appears when exposed to sunlight. Meanwhile, we said goodbye to the polluting energy technology of the past as Midwest utilities shuttered 10 fossil fuel-powered plants and
Green tech also wired the world in exciting new ways as the Smithonian Institute announced plans to replicate and share its collection with the world using 3D printing tech and a 14-year-old boy invented an incredible LEGO printer. We also watched HP launch an all-in-one workstation that pops open for easy DIY upgrades and repairs, while Huawei unveiled a soaring Pegasus sculpture made from 3,500 smartphones. Last but not least we brought you a look at Google's new Terminator-style augmented vision goggles, and we shared a fun tutorial on geocaching with your children.
Inhabitat's Week in Green: i-oniq hybrid, spherical solar cell and a incredible LEGO printer originally appeared on Engadget on Sun, 04 Mar 2012 18:00:00 EDT. Please see our terms for use of feeds.
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Sunday, March 4, 2012
Anonymous, Decentralized and Uncensored File-Sharing is Booming [Piracy]
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Saturday, March 3, 2012
Apple admits to using Corning glass for iPhone
Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/Xb4oOAiziF0/story01.htm
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Study reveals basic molecular 'wiring' of stem cells
Despite the promise associated with the therapeutic use of human stem cells, a complete understanding of the mechanisms that control the fundamental question of whether a stem cell becomes a specific cell type within the body or remains a stem cell has?until now?eluded scientists.
A University of Georgia study published in the March 2 edition of the journal Cell Stem Cell, however, creates the first ever blueprint of how stem cells are wired to respond to the external signaling molecules to which they are constantly exposed. The finding, which reconciles years of conflicting results from labs across the world, gives scientists the ability to precisely control the development, or differentiation, of stem cells into specific cell types.
"We can use the information from this study as an instruction book to control the behavior of stem cells," said lead author Stephen Dalton, Georgia Research Alliance Eminent Scholar of Molecular Biology and professor of cellular biology in the UGA Franklin College of Arts and Sciences. "We'll be able to allow them to differentiate into therapeutic cell types much more efficiently and in a far more controlled manner."
The previous paradigm held that individual signaling molecules acted alone to set off a linear chain of events that control the fate of cells. Dalton's study, on the other hand, reveals that a complex interplay of several molecules controls the "switch" that determines whether a stem cell stays in its undifferentiated state or goes on to become a specific cell type, such as a heart, brain or pancreatic cell.
"This work addresses one of the biggest challenges in stem cell research?figuring out how to direct a stem cell toward becoming a specific cell type," said Marion Zatz, who oversees stem cell biology grants at the National Institutes of Health's National Institute of General Medical Sciences, which partially supported the work.
"In this paper, Dr. Dalton puts together several pieces of the puzzle and offers a model for understanding how multiple signaling pathways coordinate to steer a stem cell toward differentiating into a particular type of cell. This framework ultimately should not only advance a fundamental understanding of embryonic development, but facilitate the use of stem cells in regenerative medicine."
To get a sense of how murky the understanding of stem cell differentiation was, consider that previous studies reached opposite conclusions about the role of a common signaling molecule known as Wnt. About half the published studies found that Wnt kept a molecular switch in an "off" position, which kept the stem cell in its undifferentiated, or pluripotent, state. The other half reached the opposite conclusion.
Could the same Wnt molecule be responsible for both outcomes? As it turns out, the answer is yes. Dalton's team found that in small amounts, Wnt signaling keeps the stem cell in its pluripotent state. In larger quantities, it does the opposite and encourages the cell to differentiate.
But Wnt doesn't work alone. Other molecules, such as insulin-like growth factor (Igf), fibroblast growth factor (Fgf2) and Activin A also play a role. To complicate things further, these signaling molecules amplify each other so that a two-fold increase in one can result in a 10-fold increase in another. The timing with which the signals are introduced matters, too.
"One of the things that surprised us was how all of the pathways 'talk' to each other," Dalton said. "You can't do anything to the Igf pathway without affecting the Fgf2 pathway, and you can't do anything to Fgf2 without affecting Wnt. It's like a house of cards; everything is totally interconnected."
Dalton and his team spent a painstaking five years creating hypotheses about the how the signaling molecules function, testing those hypotheses, and?when faced with an unexpected result?rebuilding their hypotheses and re-testing. This process continued until the entire system was resolved.
Their finding gives scientists a more complete understanding of the first step that stem cells take as they differentiate, and Dalton is confident that the same approach can be used to understand subsequent developmental steps that occur as the cells in an embryo divide into ever-more specific cell types.
"Hopefully this type of approach will give us a greater understanding of cells and how they can be manipulated so that we can progress much more rapidly toward the routine use of stem cells in therapeutic settings," Dalton said.
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University of Georgia: http://www.uga.edu
Thanks to University of Georgia for this article.
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Source: http://www.labspaces.net/118062/Study_reveals_basic_molecular__wiring__of_stem_cells
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Friday, March 2, 2012
More Peaceful Parenting. Step 1. Forgive, accept, and love yourself ...
(Photos by Sage.)
Wow. This post was harder than I ever imagined to begin. Because I am thinking: Seriously? Who am I to offer advice on a subject such as this?
Who am I?
I am a mother. A daughter. A granddaughter. A wife. A daughter-in-law. A friend. A neighbor. I am an observer and a participant in both the story of violence and the story of intentional non-violence.
And I am selective as to which tradition I choose to pass on.
Indeed, I have lived the legacy of both peaceful and non-peaceful parenting from many vantage points. And I'm ready to step up and start writing a new story. Starting today.
From the comments on the earlier posts (both this one and this one) I know I've touched a nerve. And I've lost nights of sleep over worrying that someone out there feels judged and criticized by my words. And then today in the mail (the actual mail. With a stamp and paper and everything) came a note saying (among other things), "P.S. Thanks for trying and trying to get the point across about kids and respect. I think it's a big deal."
Thanks, B. I do too.
I think it's a ginormous deal. And no matter where we've been or where it looks like we're heading, we can make changes that better the lives of our children and ourselves. How empowering is that? We get to step up and take control of our choices. We're in charge! Awesome.
But before I dig in, just to be clear, I am not:
- An abuse counselor
- A psychologist - child or otherwise
- A person living with physical, emotional, or sexual violence
- A child living with violence
- A parent wresteling with depression or mental illness
- A person healing from major past trauma
I am simply, a mom. And a mom who believes that I can do better today than I did yesterday. If you are dealing with major trauma please seek help beyond this space. Here I am simply sharing my thoughts on bringing a bit more peace into your home.
Most importantly, my words are offered without judgement for where you are or where you've been; what you've said or what you've done. They are offered with hope and gratitude for where you have chosen to go from here. What an amazing gift for yourself, your family, and the future.
While I intended to start with how you think about, speak to, or otherwise engage your child, I realized that was premature. Because before our child there was us. And that story is woven deep within our story with our own children. So perhaps the first step will be the hardest one of all.
Step 1: Forgive, accept, and unconditionally love yourself.
And when you've got that one down then move on to loving, forgiving, and accepting your parents. And your child. "Oh, right. That," you say. "No problem."
Er, or not.
Because our family stories are thick with unhealed wounds. We carry them. We play them out in a new context. We remember them in every cell. Even what we choose to forget come bubbling up during times of stress.
And so I ask you to begin by doing something that may seem nearly impossible.
Why start with love, forgiveness, and acceptance? Because it's the foundation of what we're setting out to create. It's allowing ourselves, our parents, and our child to be imperfect. And within that imperfection to still be loved and accepted. Unconditionally. Think about that for a moment. Unconditional love. Isn't that a beautiful concept? We are separate from our actions. We are loved, even when we're acting like monsters. We matter, even when we don't think we should.
It's beautiful.
If you'd like some homework, grab a blank notebook and jot down three things you appreciate about yourself every night before you go to sleep. Three gifts you bring. Three bits of your sparkle. Because guess what? You were born to shine, too.
Edited to say: Please do this exercise, with our without the pencil and paper. I did it last night in my head before I fell asleep. And while I was slow starting, I came up with three things. I know you can too.
For the very brave, share it here too. (Not required, just gutsy.) Need more inspiration? This is fantastic. No go find your awesome.?
So much love,
Rachel
?
?
Source: http://lusaorganics.typepad.com/clean/2012/02/more-peaceful-parenting-step-1-1.html
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Payday loan program for a bad credit score people | Internet ...
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