Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/281492856?client_source=feed&format=rss
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Thursday, January 31, 2013
McCain hammers Hagel on Iraq troop surge
Republican Sen. John McCain angrily dismissed defense secretary nominee Chuck Hagel as stubbornly camped ?on the wrong side? of history when it comes to Iraq, and he openly doubted whether he could support the confirmation of his former comrade and fellow Republican. The heated exchange between the two men, both decorated Vietnam War veterans, was the most notable in a series of testy verbal duels as Hagel faced some of his fiercest critics in the Senate.
McCain welcomed the former senator by saying he was ?pleased to see an old friend? before the Senate Armed Services Committee, but he immediately ripped into ?the quality of your professional judgment.? (Politico?s David Chalian noted on Twitter that the Arizona lawmaker?s tone suggested that ?old friend? really meant ?ex-friend.?)
McCain, a champion of the troop surge in Iraq, hammered Hagel over his opposition to that escalation of the war and demanded Hagel admit that he was wrong to warn it could turn out to be a Vietnam-level debacle. After labeling Hagel?s concerns ?bizarre? and ?nonsense,? McCain demanded to know whether the nominee stood by his criticisms and asked, ?Were you right or wrong about the surge??
?I stand by 'em because I made 'em,? Hagel replied. ?I would defer to the judgment of history.?
As Hagel offered to ?explain? his remarks, McCain cut him off: ?I want to know whether you were right or wrong. That?s a direct question; I expect a direct answer.?
?The surge assisted in the objective,? Hagel said. ?But if we review the record a little bit ..."
?Will you please answer the question?? McCain jumped in. ?Were you correct or incorrect when you said that the surge would be the most dangerous foreign policy blunder in this country since Vietnam? Were you correct or incorrect? Yes or no?
?Were you right or wrong? That?s a pretty straightforward question,? McCain said.
?I?m not going to give you a yes or no answer,? Hagel said. ?If you would like me to explain why ...?
?No, I actually would like an answer, yes or no,? McCain said, cutting him off.
?I?ll defer that judgment to history,? Hagel repeated. But he added that his Vietnam comments referred to ?the overall war of choice, going into Iraq? and he called the March 2003 invasion ?the most fundamentally bad, dangerous decision since Vietnam.?
?History has already made a judgment about the surge, sir, and you?re on the wrong side of it,? McCain said. ?And your refusal to answer whether you were right or wrong about it is going to have an impact on my judgment as to whether to vote for your confirmation or not.?
?I hope you will reconsider,? McCain said.
Both McCain and Hagel voted in favor of going to war in Iraq, but Hagel later turned sharply against the conflict, often echoing then-Sen. Barack Obama's accusation that the invasion diverted resources from Afghanistan.
Republicans battered Hagel on his past opposition to unilateral economic sanctions against Iran (he has said multilateral sanctions are more effective), and they repeatedly hit him on a report that he co-authored that calls for the elimination of nuclear weapons. He countered that Republican icon Ronald Reagan also favored ridding the world of atomic arsenals, and he insisted that the report was merely suggesting a possible approach, not ?unilateral? disarmament.
Much of the Republican questioning focused on Hagel?s personal policy views, not the Obama administration policies he would be implementing.
Republican Sen. Lindsey Graham of South Carolina zeroed in on Hagel?s contention that the ?Jewish lobby? intimidated American lawmakers into doing dumb things. Under Graham?s pointed questioning, Hagel acknowledged he could not name a specific lawmaker?or a single dumb thing.
Questioned by Republican Sen. Saxy Chambliss of Georgia, Hagel said Iran?s government was ?an elected, legitimate government, whether we agree or not.? (The United States does not have an embassy in Iran, but it negotiates with Tehran as part of six-country talks on that country?s nuclear program. And Washington has repeatedly criticized Iran?s elections as fixed by the country?s religious leadership.)
Confirmation hearings?much like formal debates on the Senate floor?don?t typically change senators? minds. Hagel?s confirmation, or defeat, was being played out behind the scenes as lawmakers measured the likely impact on their political fortunes. It was unclear whether Hagel would lay to rest questions about his views on Israel and Iran.
The Senate confirms Cabinet secretaries by simple majority. But 60 votes are needed if Republicans opt to throw up procedural roadblocks to delay?or kill?the nomination. Democrats, with their independent allies, have a 55-45 advantage in the Senate. To date, the only Republican to come out publicly as a ?yes? vote has been Sen. Thad Cochran of Mississippi.
Earlier, Hagel pleaded with senators not to judge him based on controversial past remarks?like his warning against the ?Jewish lobby??or on single votes he cast during his Senate career.
?No one individual vote, no one individual quote, no one individual statement defines me, my beliefs, or my record,? Hagel said in his opening remarks.
The former senator from Nebraska faces fierce opposition from some Republicans who say he would undermine America?s national security ties to Israel and does not take the threat posed by Iran?s nuclear program seriously enough. Hagel is expected to be confirmed?but not without a fight.
Republican Senate Minority Leader Mitch McConnell told Yahoo News in an exclusive interview on Wednesday that he disagreed with Hagel on a range of issues, but he called Hagel a ?smart, capable guy? who deserves a full hearing. And even some of Hagel's most forceful opponents, like Republican Sen. John Cornyn of Texas, have to date stopped short of vowing to filibuster his nomination.
Sen. Jim Inhofe of Oklahoma, the top Republican on the committee, charged that Hagel would promote "a worldview that is predicated on appeasing our adversaries while shunning our friends" and bluntly called him "the wrong person to lead the Pentagon at this perilous and consequential time."
In his remarks, Hagel took aim directly at some of his critics?and sought to reassure lawmakers who might be on the fence.
?I will ensure our friend and ally Israel maintains its Qualitative Military Edge in the region and will continue to support systems like Iron Dome, which is today saving Israeli lives from terrorists' rocket attacks,? he said.
"I am fully committed to the president?s goal of preventing Iran from obtaining a nuclear weapon, and?as I?ve said in the past, many times?all options must be on the table to achieve that goal," he said, using diplomatic language that refers to the use of military force. "My policy has always been the same as the president?s?one of prevention, and not one of containment?and the president has made clear that is the policy of our government."
Hagel's years in the Senate haven't endeared him to many Republican lawmakers still smarting over his outspoken criticism of the Iraq war even after he voted to authorize the U.S. invasion. Hagel's position on the war sealed his reputation as a party outsider and led him to lend tacit support to President Barack Obama during the 2008 presidential campaign.
Hagel has been criticized for opposing unilateral U.S. sanctions against Iran in the past?a position he now embraces?and calling for direct talks between Tehran and Washington without preconditions. He has also raised questions about his support for Israel and at one point criticized the "Jewish lobby? as having too much clout in Washington.
"Like each of you, I have a record. A record I am proud of, not because of any accomplishments I may have achieved or an absence of mistakes, but rather because I?ve tried to build that record by living my life and fulfilling my responsibilities as honestly as I knew how and with hard work," the former senator said.
"My overall worldview has never changed: that America has and must maintain the strongest military in the world; that we must lead the international community to confront threats and challenges together; and that we must use all tools of American power to protect our citizens and our interests. I believe, and always have, that America must engage?not retreat?in the world. My record is consistent on these points."
Hagel, who earned two Purple Hearts in Vietnam and still carries shrapnel in his chest, would be the first former enlisted soldier to head the Pentagon.
He was introduced by two retired senators with long careers on the committee: Democrat Sam Nunn of Georgia and Republican John Warner of Virginia. After a lengthy opening tribute, Warner got laughs from the room when he turned to Hagel and declared: "You're on your own. Good luck!"
Source: http://news.yahoo.com/blogs/ticket/hagel-don-t-judge-jewish-lobby-quote-151318895--politics.html
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Wednesday, January 30, 2013
Prince Charles takes first "Tube" trip since 1986
LONDON (Reuters) - Four million Londoners cram onto the city's Underground passenger railway nearly every day, but it is a rarer event for Prince Charles. He rode the British capital's bustling commuter network on Wednesday for the first time since 1986.
The heir to the British throne and his wife Camilla took a one-stop journey from Farringdon to King's Cross on the Metropolitan Line as part of celebrations to mark the 150th anniversary of a transport service affectionately known to Britons as the "Tube".
The short journey was a rare enough event to cause some confusion at the prince's press office, which initially said he had last ventured onto the Tube in 1979.
"This is just to let you know that it has come to our attention that The Prince of Wales has travelled on the London Underground more recently than 1979. In 1986 The Prince and Princess of Wales travelled by tube to Heathrow Airport to open Terminal 4," a spokeswoman said in an email to media.
"We're sorry that our previous information was incorrect. Our archives of Royal engagements prior to 1988 are not computerised and in this particular instance a search under 'The Prince of Wales takes the Tube' did not bring up an event which had been logged as the 'official opening of Terminal 4'."
(Reporting By Estelle Shirbon, editing by Paul Casciato)
Source: http://news.yahoo.com/prince-charles-takes-first-tube-trip-since-1986-184006782.html
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Alicia Keys is BlackBerry's new Global Creative Director -- yep
If you didn't get the hint from the constant appearances during the BlackBerry 10 video promos, BlackBerry loves Alicia Keys. And it looks like she might like it back. Filled with analogies of new lovers and "exclusively dating" a mobile platform, Alicia Keys is now BlackBerry's Global Creative Director. We're not sure what her work remit will be (although there was a mention of app development) but we presume Will.I.Am is somewhere, crying in a pool of money.
Other famous fans that BlackBerry mentioned on stage include Neil Gaiman and Robert Rodriguez -- creative types are looking forward to their new free BlackBerry phone.
Filed under: Cellphones, Mobile, RIM
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/nkykuH03Tuk/
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Rdio promises up to six months of free streaming in more countries
What's better than free music? Lots of stuff, probably -- but it's still on the top of our list. Rdio is hoping to get you hooked into its vowel-agnostic music streaming ways with the promise of "up to six months of free music" without ads or credit card numbers. The deal adds a number of countries to the list (of which the US is already a member) -- including the UK, Australia, Canada, France and Spain. There are 15 in total (again, already including the US). Germany and Brazil are sadly still excluded from the free music party. While the offering is ad-free, each month does include a limited number of plays (though Rdio's not giving an exact number at the moment), which will count down on your page. More info on the offering can be found after the break.
Rdio Launches Free Music Streaming in Nearly All Countries Where Rdio is Available
Rdio, (www.rdio.com), the streaming music service from the co-creator of Skype, is now offering music lovers up to six months of free music on the Web in nearly all countries where Rdio is available1. New Rdio listeners can sign up and activate free streaming at rdio.com, with no credit card required, then dive right into Rdio's library of over 18 million songs.
This new offer is specifically designed to appeal to people with ears and hearts. Free streaming is available through the Web or Rdio's desktop apps for Mac and Windows, and allows listeners to:
? Choose from over 18 million songs, without ads
? Listen free on the web for up to six months, depending on how many songs you stream
? See and hear what your favorite artists are listening to
? Discover new music by following friends and tastemakers
? Create, curate, and collaborate on playlists
? Share your life soundtrack in real time on Facebook and Twitter
A meter at the top of user profile pages lets people know how much free music they have remaining each month. It's easy to upgrade any time to one of Rdio's subscription plans for unlimited streams and access to Rdio's acclaimed mobile apps. US plan options include:
? Rdio Web: $4.99 a month. Unlimited Web streaming.
? Rdio Unlimited: $9.99 a month. Unlimited Web and mobile streaming, as well as wireless syncing to listen offline.2
Music fans can sign up for free Rdio streaming right now at www.rdio.com.
Filed under: Internet, Software
Source: http://www.engadget.com/2013/01/28/rdio-free-streaming/
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Tuesday, January 29, 2013
Pregnant women should get whooping cough shot: CDC
NEW YORK (Reuters Health) - Moms-to-be should get a booster tetanus, diphtheria and pertussis (Tdap) vaccine during each pregnancy to help protect their infants from whooping cough, according to a new vaccine schedule released today by the Centers for Disease Control and Prevention (CDC).
Babies don't get their first pertussis vaccine until two months of age - and even then, they aren't fully protected until after their third shot, at six months. In the interim, they are at especially high risk of getting very sick from the bacterial disease.
During a 2010 whooping cough outbreak in California, for example, more than 9,000 cases were reported and 10 infants died.
Vaccinating pregnant women serves the dual purpose of keeping moms from contracting whooping cough and passing it to their infants as well as allowing some immune cells to pass to babies through the placenta.
"It turns out that immunity wanes pretty quickly," said Dr. H. Cody Meissner, a pediatrician from the Tufts University School of Medicine in Boston who is on the CDC's immunization committee.
"Without boosting with each pregnancy, a mother's immunity will wane and she will have much less immunity to pass on to the baby," Meissner told Reuters Health.
COCOONING
Although not part of the new immunization schedule, experts recommend immunizing a new baby's father, siblings and other caretakers. That strategy is known as cocooning.
"It's a good time to make sure that everyone who will be caring for the child is also up to date on their vaccines," said Dr. Daniel McGee, a pediatrician with Helen DeVos Children's Hospital in Grand Rapids, Michigan, who wasn't involved in the new guidelines.
"You need to make sure if grandma and grandpa are coming to visit, they're protected as well," he told Reuters Health.
Along with the new guidelines for pregnant women, updates to the CDC's vaccination schedule include a routine Tdap shot for adults age 65 and older and a pneumococcal vaccine approved for adults with immune compromising conditions like kidney failure.
Some children who are ill, such as with sickle cell disease, should get meningococcal vaccines starting at two months of age, according to the schedule. Other kids don't have to start those shots until middle school.
The influenza vaccine is still recommended annually, but will now protect against four strains of flu rather than three, said Erin Kennedy, a medical epidemiologist at the CDC.
Parents should educate themselves as best they can on recommended vaccines, researchers said.
"It's quite complicated, and it does change all the time. But it's imperative for people to stay up to date and informed about which vaccines are available," Meissner said.
"There are 16 vaccine preventable diseases that children receive immunizations against in the first 18 years of life," he added. "If vaccination rates fall, we're going to see increases in some of these diseases."
Because the immunization program has focused on children, Kennedy said some adults don't know the schedule also calls for them to get a range of vaccinations based on their age, health or where they travel.
"Adults need to be aware of the fact that there are vaccines that are recommended throughout the lifespan," she told Reuters Health. "Right now coverage is low for all of these vaccines."
Updates to the CDC's vaccination schedule were published concurrently on Monday in Pediatrics and the Annals of Internal Medicine.
SOURCES: http://bit.ly/cxXOG Pediatrics and http://bit.ly/MnBiCA Annals of Internal Medicine, online January 28, 2013.
Source: http://news.yahoo.com/pregnant-women-whooping-cough-shot-cdc-220405935.html
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Video: Finding common ground on immigration
>>> in washington this evening, here's something we haven't been able to say in a long time. there is new hope for a broad bipartisan agreement, this time on the issue of immigration reform . after republicans took a historic shellacking among hispanic voters in the november election, what has been one of the most divisive issues in recent politics, suddenly has lawmakers on both sides ready to make some sort of a deal. kelly o'donnell following it all for us on capitol hill tonight. kelly , good evening.
>> reporter: good evening, brian. there really is new political urgency driving this. republicans say immigration reform is one way they could better connect with the fast-growing block of hispanic voters. democrats would like to help the president get an early second term success. so all that makes an agreement hammered out this weekend look like it's got a shot to deal with the 11 million people believed to be here illegally. today, in places like this vegetable field in ventura county , california, the immigration struggle is part of daily life for farmer craig underwood and 200 my grant workers he hires.
>> we would hope for some sort of reform, so that the workers don't feel threatened and that we don't feel threatened.
>> reporter: in a new plan, senators from both parties agreed, to get a green card and years later, citizenship, undocumented immigrants would register with the federal government , pay fines and back taxes, undergo criminal background checks and learn english. while other attempts at reform have failed, they claim this time is different.
>> the public's attitude has changed in four years. four years ago, they said, fix the border. now they much prefer a comprehensive solution.
>> elections. elections. the republican party is losing the support of our hispanic citizens.
>> reporter: a voting block so critical -- in an unusual display, both a veteran democrat and rising star republican described the plan in spanish. [ speaking in spanish ]
>> reporter: to attract conservatives, promises to strengthen security. more border patrol agents and aerial drone surveillance. the government would track temporary visas to reduce staying past deadlines and create a new employment verify verification system.
>> we have to ensure we don't do anything that encourages people to come here illegally in the future.
>> so there are new rules for undocumented immigrants who fill special needs . an agricultural worker program would permit laborers to work in the u.s. legally, but does not grant citizenship. visiting students who earn advanced degrees in science and technology here could get a green card . and, of course, there is real resistance among some republicans and some democrats. so the people behind this plan say they know it will still be very tough to turn today's framework into specifics and to get something done. brian?
>> kelly o'donnell on the hill covering it all for us tonight. kelly , thanks. let's bring
Source: http://video.msnbc.msn.com/nightly-news/50620836/
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Senators Unveil Framework for Immigration Reform - Politics - CBN ...
"Tough" but "fair," that's how a bipartisan group of Senators is describing their framework for comprehensive immigration reform.
The plan boosts border security, requires employers to verify the legal status of workers, and ties legal immigration allowances to the U.S. Economy.
The proposal also includes a path to citizenship for illegal immigrants already in the U.S.
The group wants to pass an immigration bill by summer.
And proponents of comprehensive reform say it's long overdue.
"The vast majority of Americans believe that we need to have a legal immigration system that works, and they recognize that what we have now is not a 21st century legal immigration system," said Sen. Marco Rubio, R-Fla.
"It is quite within reach for us to reach a consensus in this country that can do justice for millions of people but equally important can make our economy and our democracy be what it really should be," said Hector Figuero, immigration advocate.
On Tuesday President Obama travels to Las Vegas to drum up public support for immigration reform.
Source: http://www.cbn.com/cbnnews/politics/2013/January/Senators-Unveil-Framework-for-Immigration-Reform1/
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Monday, January 28, 2013
Aaron shakes up US men's skating with 1st title
OMAHA, Neb. (AP) ? Never mess with the guy who knows how to rumble.
Little-known Max Aaron won his first title at the U.S. Figure Skating Championships on Sunday and helped knock down three-time champion Jeremy Abbott to the last step on the podium. With two quadruple jumps and an arsenal's worth of other tricks in his "West Side Story" program, don't count the 20-year-old upstart out at the world championships in March, either.
"I kind of thought in the back of my mind he could be the national champion," coach Tom Zakrajsek said. "There are so many great men and you never know how they're going to skate or how it's going to be judged. I did think he gave a performance today ? when you give a performance like that, it's worthy of a national title.
"He skated into the title, which is kind of a nice way to earn it."
Aaron screamed and shook his fists when he finished his program, then slid across the ice giving a Tiger Woods-like fist pump. (He was wearing red, appropriately, and it was Sunday.)
"The goals I had coming into this event were just to complete two clean programs. I didn't think of ever medaling," Aaron said. "But I knew if I completed the programs the way I know I can do them, I knew I could be up there."
When his marks were posted, Aaron's jaw dropped and the audience roared. He won the free skate in a rout to jump from fourth to first, and finished with 255 points overall, almost four better than Ross Miner.
Abbott, who had won three of the last four U.S. titles, dropped to third after a disappointing and flawed free skate. The Americans can only send two men to the world championships, so Abbott will have to watch and hope Aaron and Miner do well enough to get an extra spot for the Sochi Olympics.
"These two men skated brilliantly and they deserve to be in the positions they are," Abbott said. "Not to put any pressure on them, but they better get three spots for next year."
Aaron was the U.S. junior champ two years ago, but has done little of note since then. He actually considered quitting skating last summer, after he finished eighth at nationals.
Skating first of the top men, however, he wasted no time letting everyone know he's got the makings of a champion. He opened with two quadruple salchows, the first in combination with a double toe loop, and did seven triples. Aside from a small turn out on a triple axel, his jumps were done with such great speed and flow people watching at home on their couches were probably saying, "That doesn't look so hard, I could do that."
Aaron is more than just a jumping bean, however. His spins were excellent, so fast and tightly centered he was practically a blur. He jazzed up his footwork with high kicks and hops, the kind of flourishes audiences ? and judges ? love.
But it was his perfect portrayal of the bad boy in "West Side Story" that was most entertaining. As he heard the first notes of his music, he fixed the audience with a smirk and began snapping his fingers. He oozed attitude throughout the entire program, so much so it's a wonder the Jets didn't storm the ice and try and wipe the smile from his face.
"This wasn't just a performance that happened. This is how he trains," Zakrajsek said. "Our big goal was just to deliver what he trained and see how he fit in."
Aaron's big score in the free skate ? 175.87 ? was going to be tough for Abbott, Miner and the rest of the guys to top. No one came close.
Miner has quietly developed into one of the most reliable U.S. men, finishing third at the previous two nationals and winning a bronze at this year's NHK Trophy. That's bolstered his confidence, and he's skating with more polish and assertiveness than ever before. Every element in his program, to the old "Captain Blood" movie, was finished to perfection. There was no rushing out of jumps or awkward ends to spins.
It's the kind of precision a skater has to have if he's to contend with the international crowd.
He, too, did a quad salchow ? a gorgeous one, to boot ? and seven other triple jumps. His only flaw was singling an axel, a silly mistake that's sure to nag at him until next year's nationals.
"The single axel is not what I was looking for, but I'm happy I kept my head in it and fought all the way to the end," Miner said. "It was a good day."
Not for Abbott, whose program was barely adequate technically for a skater of his caliber.
He was so slow on the approach to his quadruple toe it looked as if he was going to stop and, no surprise, he landed on his rear end. But it was his other jumps that were more disappointing. His landings were scratchy and awkward, a shock for a skater who prides himself on his skating skills, including edge quality so fine the carvings could be sold as artwork.
He still might have finished ahead of Miner had he not popped his final jump, turning a planned triple salchow into a double. He skated off the ice banging his forehead with his fist.
"Stupid bleeping triple sal," Abbott said of what he was thinking. "When I doubled it, I knew that was going to be the difference. It's the easiest jump in the program, and I let it go. I knew at that point I going to be just enough behind."
Source: http://news.yahoo.com/aaron-shakes-us-mens-skating-1st-title-222853947--spt.html
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First guidelines for brain amyloid imaging in Alzheimer's released
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Public release date: 28-Jan-2013[ | E-mail |
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Society of Nuclear Medicine
CHICAGO, January 28, 2013 Only recently has it become possible to create high-quality images of the brain plaques characteristic of Alzheimer's disease in living people through positron emission tomography (PET). Even so, questions remain about what can be learned from these PET images and which people should have this test.
To provide guidance for physicians, individuals and families affected by Alzheimer's, and the public, the Society of Nuclear Medicine and Molecular Imaging (SNMMI) and the Alzheimer's Association have jointly published the first criteria for the appropriate use of this imaging technology to aid in the diagnosis of people with suspected Alzheimer's disease. The criteria were published online today as an article "in press" by Alzheimer's & Dementia: The Journal of the Alzheimer's Association and "ahead of print" in The Journal of Nuclear Medicine.
"Our primary goal is to provide healthcare practitioners with the information and options available to provide patients with the best possible diagnosis and care in a cost effective manner," said Maria Carrillo, Ph.D., Alzheimer's Association vice president of Medical and Scientific Relations.
Appropriate Use Criteria (AUC) for Brain Amyloid Imaging with PET in Alzheimer's
While elevated beta amyloid plaques are one of the defining pathologic features of Alzheimer's, many elderly people with normal cognition also have elevated levels of these plaques, as do people with conditions other than Alzheimer's dementia. Therefore, the potential clinical use of amyloid PET requires careful consideration so that its proper role may be identified.
To develop the new criteria, the Alzheimer's Association and SNMMI assembled an Amyloid Imaging Taskforce (AIT) consisting of dementia and imaging experts to review the scientific literature and develop consensus recommendations for the clinical use of this promising new technology.
The AIT concluded that amyloid imaging could potentially be helpful in the diagnosis of people with cognitive impairment when considered along with other clinical information, and when performed according to standardized protocols by trained staff. In addition, they emphasized that the decision whether or not to order amyloid imaging should be made only after a comprehensive evaluation by a physician experienced in the assessment and diagnosis of cognitive impairment and dementia, and only if the presence or absence of amyloid would increase certainty in the diagnosis and alter the treatment plan.
According to the AIT, appropriate candidates for amyloid PET imaging include:
- Those who complain of persistent or progressive unexplained memory problems or confusion and who demonstrate impairments using standard tests of cognition and memory.
- Individuals meeting tests for possible Alzheimer's, but who are unusual in their clinical presentation.
- Individuals with progressive dementia and atypically early age of onset (before age 65).
Inappropriate candidates for amyloid PET imaging include:
- Those who are age 65 or older and meet standard definitions and tests for Alzheimer's, since a positive PET scan would provide little added value.
- Asymptomatic people or those with a cognitive complaint but no clinical confirmation of impairment.
Amyloid PET imaging is also inappropriate:
- As a means of determining the severity of dementia.
- When requested solely based on a family history of dementia or presence of other risk factors for Alzheimer's, such as the ApoE-e4 gene.
- As a substitute for genetic testing for mutations that cause Alzheimer's.
- For non-medical reasons, such as insurance, legal or employment decisions.
"As amyloid imaging becomes more prevalent in clinical settings, medical professionals must understand how to appropriately utilize the test," said Frederic H. Fahey, D.Sc., SNMMI president. "Neurology and dementia experts should order the test only when appropriately indicated, and nuclear medicine and molecular imaging professionals must ensure they have been adequately trained to interpret the results of the scan. Working together, we hope that the information garnered from amyloid PET imaging will aid in diagnosis and play a pivotal role in the development of new treatments for Alzheimer's."
The taskforce acknowledged that the healthcare provider makes the ultimate judgment regarding the care of each patient. The AIT sought to assist this process and identified the following general sequence of events for the use of amyloid PET according to the new criteria:
- Evaluation by a dementia expert to assess the need for diagnostic testing, possibly to include amyloid PET if the AUC are met.
- Referral to a qualified provider of amyloid PET services.
- Performance, interpretation and reporting of the amyloid PET scan according to established standards.
- Incorporation of the PET result into the clinical assessment process.
- Disclosure of the PET result by the clinician to the patient and caregivers, along with discussion of the result and its management consequences.
Although identifying potential benefits, the AIT concluded that amyloid PET results will not constitute and is not equivalent to a clinical diagnosis of Alzheimer's disease dementia. They said that imaging is only one tool among many that clinicians should use judiciously to manage patients, and that amyloid PET imaging does not substitute for a careful history and examination.
"Because both dementia care and amyloid PET technology are in active development, these new appropriate use criteria will require periodic reassessment and updating," Carrillo said.
PET Amyloid Imaging in Alzheimer's An Overview
PET uses radiopharmaceuticals (radioactive drugs) to produce three-dimensional functional images of the brain or other body part. In amyloid PET imaging, the radiopharmaceutical is introduced into the body by injection into a vein and binds specifically to the amyloid protein, enabling visualization of areas in the brain where amyloid has clumped together into plaques. One of the new PET compounds was approved for general use by the U.S. Food and Drug Administration in April 2012.
- If a person with dementia does not have amyloid buildup in their brain, then the cause of the dementia is very likely to be something other than Alzheimer's disease. Other causes of dementia include: strokes, thyroid problems, drug interactions, chronic alcoholism, and vitamin deficiencies.
- If an amyloid imaging PET scan shows that a person with memory impairment has amyloid buildup in their brain, this increases the likelihood that the memory impairment is caused by Alzheimer's disease, but it remains a likelihood, not a certainty.
- If a person without memory complaints or impairment has amyloid buildup, it does not necessarily mean that they will develop Alzheimer's. Many people have amyloid in their brains but are cognitively normal. More research is needed to understand the significance of amyloid plaques in this population.
Amyloid imaging is not covered by insurance at this time, and costs for the scan are "out of pocket." While costs of amyloid PET are not yet established, and PET costs in general can vary depending upon location, other PET scans are known to cost between $1,000 and $3,000, or more. Nonetheless, the AIT concluded that the proven sensitivity and specificity of the new radiopharmaceuticals for brain amyloid and the known association between brain beta amyloid deposition and Alzheimer's suggest these new radiopharmaceuticals could potentially be helpful in the workup and diagnosis of patients with cognitive impairment.
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Public release date: 28-Jan-2013[ | E-mail |
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Society of Nuclear Medicine
CHICAGO, January 28, 2013 Only recently has it become possible to create high-quality images of the brain plaques characteristic of Alzheimer's disease in living people through positron emission tomography (PET). Even so, questions remain about what can be learned from these PET images and which people should have this test.
To provide guidance for physicians, individuals and families affected by Alzheimer's, and the public, the Society of Nuclear Medicine and Molecular Imaging (SNMMI) and the Alzheimer's Association have jointly published the first criteria for the appropriate use of this imaging technology to aid in the diagnosis of people with suspected Alzheimer's disease. The criteria were published online today as an article "in press" by Alzheimer's & Dementia: The Journal of the Alzheimer's Association and "ahead of print" in The Journal of Nuclear Medicine.
"Our primary goal is to provide healthcare practitioners with the information and options available to provide patients with the best possible diagnosis and care in a cost effective manner," said Maria Carrillo, Ph.D., Alzheimer's Association vice president of Medical and Scientific Relations.
Appropriate Use Criteria (AUC) for Brain Amyloid Imaging with PET in Alzheimer's
While elevated beta amyloid plaques are one of the defining pathologic features of Alzheimer's, many elderly people with normal cognition also have elevated levels of these plaques, as do people with conditions other than Alzheimer's dementia. Therefore, the potential clinical use of amyloid PET requires careful consideration so that its proper role may be identified.
To develop the new criteria, the Alzheimer's Association and SNMMI assembled an Amyloid Imaging Taskforce (AIT) consisting of dementia and imaging experts to review the scientific literature and develop consensus recommendations for the clinical use of this promising new technology.
The AIT concluded that amyloid imaging could potentially be helpful in the diagnosis of people with cognitive impairment when considered along with other clinical information, and when performed according to standardized protocols by trained staff. In addition, they emphasized that the decision whether or not to order amyloid imaging should be made only after a comprehensive evaluation by a physician experienced in the assessment and diagnosis of cognitive impairment and dementia, and only if the presence or absence of amyloid would increase certainty in the diagnosis and alter the treatment plan.
According to the AIT, appropriate candidates for amyloid PET imaging include:
- Those who complain of persistent or progressive unexplained memory problems or confusion and who demonstrate impairments using standard tests of cognition and memory.
- Individuals meeting tests for possible Alzheimer's, but who are unusual in their clinical presentation.
- Individuals with progressive dementia and atypically early age of onset (before age 65).
Inappropriate candidates for amyloid PET imaging include:
- Those who are age 65 or older and meet standard definitions and tests for Alzheimer's, since a positive PET scan would provide little added value.
- Asymptomatic people or those with a cognitive complaint but no clinical confirmation of impairment.
Amyloid PET imaging is also inappropriate:
- As a means of determining the severity of dementia.
- When requested solely based on a family history of dementia or presence of other risk factors for Alzheimer's, such as the ApoE-e4 gene.
- As a substitute for genetic testing for mutations that cause Alzheimer's.
- For non-medical reasons, such as insurance, legal or employment decisions.
"As amyloid imaging becomes more prevalent in clinical settings, medical professionals must understand how to appropriately utilize the test," said Frederic H. Fahey, D.Sc., SNMMI president. "Neurology and dementia experts should order the test only when appropriately indicated, and nuclear medicine and molecular imaging professionals must ensure they have been adequately trained to interpret the results of the scan. Working together, we hope that the information garnered from amyloid PET imaging will aid in diagnosis and play a pivotal role in the development of new treatments for Alzheimer's."
The taskforce acknowledged that the healthcare provider makes the ultimate judgment regarding the care of each patient. The AIT sought to assist this process and identified the following general sequence of events for the use of amyloid PET according to the new criteria:
- Evaluation by a dementia expert to assess the need for diagnostic testing, possibly to include amyloid PET if the AUC are met.
- Referral to a qualified provider of amyloid PET services.
- Performance, interpretation and reporting of the amyloid PET scan according to established standards.
- Incorporation of the PET result into the clinical assessment process.
- Disclosure of the PET result by the clinician to the patient and caregivers, along with discussion of the result and its management consequences.
Although identifying potential benefits, the AIT concluded that amyloid PET results will not constitute and is not equivalent to a clinical diagnosis of Alzheimer's disease dementia. They said that imaging is only one tool among many that clinicians should use judiciously to manage patients, and that amyloid PET imaging does not substitute for a careful history and examination.
"Because both dementia care and amyloid PET technology are in active development, these new appropriate use criteria will require periodic reassessment and updating," Carrillo said.
PET Amyloid Imaging in Alzheimer's An Overview
PET uses radiopharmaceuticals (radioactive drugs) to produce three-dimensional functional images of the brain or other body part. In amyloid PET imaging, the radiopharmaceutical is introduced into the body by injection into a vein and binds specifically to the amyloid protein, enabling visualization of areas in the brain where amyloid has clumped together into plaques. One of the new PET compounds was approved for general use by the U.S. Food and Drug Administration in April 2012.
- If a person with dementia does not have amyloid buildup in their brain, then the cause of the dementia is very likely to be something other than Alzheimer's disease. Other causes of dementia include: strokes, thyroid problems, drug interactions, chronic alcoholism, and vitamin deficiencies.
- If an amyloid imaging PET scan shows that a person with memory impairment has amyloid buildup in their brain, this increases the likelihood that the memory impairment is caused by Alzheimer's disease, but it remains a likelihood, not a certainty.
- If a person without memory complaints or impairment has amyloid buildup, it does not necessarily mean that they will develop Alzheimer's. Many people have amyloid in their brains but are cognitively normal. More research is needed to understand the significance of amyloid plaques in this population.
Amyloid imaging is not covered by insurance at this time, and costs for the scan are "out of pocket." While costs of amyloid PET are not yet established, and PET costs in general can vary depending upon location, other PET scans are known to cost between $1,000 and $3,000, or more. Nonetheless, the AIT concluded that the proven sensitivity and specificity of the new radiopharmaceuticals for brain amyloid and the known association between brain beta amyloid deposition and Alzheimer's suggest these new radiopharmaceuticals could potentially be helpful in the workup and diagnosis of patients with cognitive impairment.
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Source: http://www.eurekalert.org/pub_releases/2013-01/sonm-fgf012513.php
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Zac Brown Band to perform at Daytona 500 concert
FILE - This May 4, 2012 file photo shows Zac Brown performing with the Zac Brown Band at the New Orleans Jazz and Heritage Festival in New Orleans. The Zac Brown Band will perform at the Daytona 500 season opening race on Feb. 24. (AP Photo/Gerald Herbert, file)
FILE - This May 4, 2012 file photo shows Zac Brown performing with the Zac Brown Band at the New Orleans Jazz and Heritage Festival in New Orleans. The Zac Brown Band will perform at the Daytona 500 season opening race on Feb. 24. (AP Photo/Gerald Herbert, file)
NASHVILLE, Tenn. (AP) ? Zac Brown hasn't put together the set list for his Daytona 500 kickoff concert next month, but he's got a pretty good idea of how it will go.
"It would have to be up-tempo, rockin'," Brown said, "... tryin' to get everybody pumped up for the race."
It's a pedal to the metal kind of time for the group over the next month.
First up: the Grammy Awards, where the band is up for country album of the year on Feb. 10 in Los Angeles.
Brown said band members are excited about a return to the show, where they won best new artist in 2010.
"It's the awards show. It is the one," Brown said. "The other ones, there's a lot of politics, in my opinion. This one is legitimately chosen by your peers as an artist. I think you're judged by your music at the Grammys."
Then it's on to Florida for the Feb. 24 Daytona 500, NASCAR's season-opening race. The seven-piece band will play a miniconcert during the Budweiser Pre-Race Show, with two songs aired live.
Like the Grammys, it's a milestone moment for the band. And not just musically. Brown grew up in Georgia where the Daytona 500 is as big as the Super Bowl. Maybe bigger.
"It was always the big sporting event," Brown said. "Anytime there was major championships or major races, they were usually on TV. They were usually a part of what was going on when we were all hanging out together."
___
Online:
http://zacbrownband.com
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Sunday, January 27, 2013
Adele's Father Reveals He Has No Contact With Singer: 'It's Like I'm Dead To Her'
Since he sold a story about her to the press in 2011, Mark Evans has yet to have any contact with his daughter Adele -- and he has a feeling that trend isn't going to end.
In a new interview, Evans admitted to The Daily Mail that he has had no access to Adele or her 3-month-old son and feels like she has completely shut him out of her life.
"It breaks my heart that Adele is so hell-bent on cutting me off like this. I knew she had met her new fella ... but it was a bolt out of the blue when I found out she was expecting," Evans, 49, told The Daily Mail. "As soon as I found out, I wanted more than ever to get in touch and meet up so I could see how she was with my own eyes and let her know I'm here for her."
Adele, 24, has been dating her son's father, Simon Konecki, since January of last year. Still, Evans hasn't had the chance to meet him ... and probably never will.
Evans left Adele's mother Penny when the Grammy-winning singer was three and has not had a good relationship with his daughter since. After he cashed in on the story, Adele dissed her dad, openly admitting she would never speak to him again.
"I was actually ready to start trying to have a relationship with him. He's f**king blown it. He will never hear from me again," Adele told Vogue magazine in Feb. 2012. "There's consequences other than just getting a bit of f**king money that lasts you half a year. It blows my mind. 'I love her so much.' Really? Why are you telling me that through a newspaper? If I ever see him I will spit in his face."
"I'm not interested in her celebrity status or her money, I just want my daughter back and I want to be a proper granddad to the little one," Evans, a Welsh plumber, added to The Daily Mail. "I'm missing out on so many of the joys of being a grandfather. Simple pleasures like taking him out for a walk in his buggy along the promenade at Penarth like I used to with Adele."
Also on HuffPost:
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Source: http://www.huffingtonpost.com/2013/01/27/adeles-father-dead-to-her_n_2562856.html
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Be Your Own Contractor With These Home Improvement Tips | OK ...
TIP! Use paint to decorate your home on a budget. Even if your budget has no room for a large-scale improvement project, paint can work wonders.
Not many projects are as fulfilling as home improvement projects. You can really feel pride of ownership when you dedicate time to making your home the best it can be. How do you begin? This guide will give you great tips on how to get your home to look even better.
TIP! Before you go to the home improvement center, be sure to make a complete list of necessary items. When you make a list, it will be easier for you to ensure that you don?t forget anything and have to go back to the store.
If you are renovating tile floors, consider radiant heat tiles. Radiant heat tiles use electricity to heat the tiles and keep your feet warm. Fortunately for you, these are also really easy to put in if you are able to precisely follow the instructions. This is a project that you can do yourself without any help. You will be happy you did when you go into your bathroom on that first day of winter.
TIP! Think about the amount your home?s value will increase before doing a home improvement project. You want to consider those projects that will net the greatest return on your time and money.
To make a dreary or dated looking home feel vibrant and new, repaint the walls. A fresh coat of paint can completely change the look of a room. It does not cost much to paint, and it will significantly add value to your home. Use light colors that work with your decor.
TIP! If you want to change a room and not spend a lot of money, you can paint the room utilizing a unique paint technique. It?s cheap to do such a project, while the rewards are plentiful.
Prior to starting a home improvement job, be sure to list all the actions you believe will occur from the time you start to the time you finish. When you have finished your list, show it to friends and relations who have DIY home improvement experience to make sure you haven?t left anything out. Make sure you put aside enough time to work on this project, because you never really know how long it will take to finish everything.
TIP! Before you agree to have an alarm system installed, carefully consider its advantages and disadvantages. If you spend a lot of time away from home or reside in an unsafe neighborhood, a security system is a good idea.
View things can match your home in importance to your daily life. It is also important that it looks the best it can. The tips shared here with you are excellent for keeping in mind for your projects. Consider which ones you like and create some time for you to work on them.
Source: http://okheyday.com/be-your-own-contractor-with-these-home-improvement-tips/
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Saturday, January 26, 2013
Chance finding reveals new control on blood vessels in developing brain
Friday, January 25, 2013
Zhen Huang freely admits he was not interested in blood vessels four years ago when he was studying brain development in a fetal mouse.
Instead, he wanted to see how changing a particular gene in brain cells called glia would affect the growth of neurons.
The result was hemorrhage, caused by deteriorating veins and arteries, and it begged for explanation.
"It was a surprising finding," says Huang, an assistant professor of neuroscience and neurology at the University of Wisconsin-Madison. "I was mainly interested in the neurological aspect, how the brain develops and wires itself to prepare for all the wonderful things it does."
But chance favors the prepared mind, as Louis Pasteur said, and Huang knew he needed to follow up on the suggestion that glia, normally considered "helpers" for the neurons, would affect the growth of blood vessels. For one thing, blood flow is a big deal in the brain, says Huang, whose collaborators included Shang Ma, in the graduate program in cellular and molecular biology at UW-Madison. "We know the brain is very energy-intensive. Per unit of volume, it consumes 10 times as much oxygen as the rest of the body."
Although it makes intuitive sense that blood vessel development should be guided by neuronal development in some fashion, Huang spent years making sure he wasn't being mislead by his experiment. Now, he's satisfied himself, and his scientific reviewers, and the journal PLOS Biology has just published his study.
Glial cells in the nervous system establish a nurturing environment for neurons but do not carry signals. In particular, Huang looked at "radial glial cells," which also act as stem cells in creating new neurons. Radial glia extend from the inside of the brain to the outside, and also guide growing neurons to their final locations.
A standard way to find out what cells and genes do is to "knock out" specific genes, using a technology invented at UW-Madison by former professor Oliver Smithies (who shared the 2010 Nobel Prize for this discovery).
When Huang grew mice with a "knock out" mutation that blocked cell division among the radial glia, he expected to see abnormalities in the embryonic brain. But the major abnormality was completely unexpected: blood vessels that had already formed had collapsed.
New blood vessels in an embryo generally develop via a two-step process, first growing, and then stabilizing. "If the second step cannot be carried out, the vessels may already be formed, but the organ still cannot get its blood supply because the vessel will regress, or collapse," Huang says.
When blood vessels collapse, neurons start to die, says Huang. Some brain diseases, including Alzheimer's and hemorrhagic stroke, show a similar regression, and Huang says it's possible that the signaling mechanism that he experimentally blocked may play a role in these diseases as well.
Although any clinical treatment is years away, Huang is still basking in the thrill of basic discovery.
"We find that these progenitor and helper cells, the radial glia, regulate blood vessel development, and nobody has found that before." Huang says. "We used a mouse with alterations in genetics that regulate activity in these helper cells in the brain, and were very surprised to see that this had a drastic effect on blood vessel development. Previously it was always thought that these were two separate systems, now we know there is crosstalk between them. It's almost like a new field has opened up."
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University of Wisconsin-Madison: http://www.wisc.edu
Thanks to University of Wisconsin-Madison for this article.
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Hubble finds appearances can be deceptive: Looking at the stars in NGC 411
Jan. 26, 2013 ? Globular clusters are roughly spherical collections of extremely old stars, and around 150 of them are scattered around our galaxy. Hubble is one of the best telescopes for studying these, as its extremely high resolution lets astronomers see individual stars, even in the crowded core. The clusters all look very similar, and in Hubble's images it can be quite hard to tell them apart -- and they all look much like NGC 411, pictured in a new image.
And yet appearances can be deceptive: NGC 411 is in fact not a globular cluster, and its stars are not old. It isn't even in the Milky Way. NGC 411 is classified as an open cluster located in the Small Magellanic Cloud, a small sister galaxy near our own. Less tightly bound than a globular cluster, the stars in open clusters tend to drift apart over time as they age, whereas globulars have survived for well over 10 billion years of galactic history. NGC 411 is a relative youngster -- not much more than a tenth of this age. Far from being a relic of the early years of the universe, the stars in NGC 411 are in fact a fraction of the age of the sun.
The stars in NGC 411 are all roughly the same age, having formed at one time from one cloud of gas. But they are not all the same size. Hubble's image shows a wide range of colors and brightness in the cluster's stars; these tell astronomers many facts about the stars, including their mass, temperature and evolutionary phase. Blue stars, for instance, have higher surface temperatures than red ones.
The image is a composite produced from ultraviolet, visible and infrared observations made by Hubble's Wide Field Camera 3. This filter set lets the telescope "see" colors slightly further beyond red and the violet ends of the spectrum.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/space_time/nasa/~3/nCwqd3lMSz0/130126092923.htm
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Apogee revamps One and Duet audio interfaces for iOS and Mac, updates Quartet to match
Apogee wants bring pro audio interfaces to the mobile realm. To that end, it's coming to NAMM with a trio of options that cover most Apple-bound musicians and podcasters. Its next-generation One interface (seen after the break) can take simultaneous input from both a built-in condenser mic and one device plugged into either an XLR or quarter-inch jack, passing along the resulting tunes to an iOS device or a Mac's USB port. A similarly reworked Duet adds direct iOS connections to the two-input, four-output Duet (above). Full-fledged bands aren't left out of the equation, either -- the existing, four-input Quartet has received iPad support without changing its formula. Lighting-based iOS gear unfortunately requires an adapter, but we'll take consolation in a new Maestro app for iPads that offers control over connections and session monitoring. Producers hoping for more mobility can pick up the Duet or Quartet in February at their respective $595 and $1,295 prices, although they'll have to wait until March to buy the One at $349.
Apogee Electronics introduces all new "ONE", audio interface & microphone featuring iPad & Mac compatibility, upgraded sound quality and new Maestro control app for iOS
Anaheim, California, January 24, 2013 - Apogee Electronics is pleased to introduce the completely redesigned ONE, a 2 IN x 2 OUT USB audio interface and microphone. The all new ONE is the first studio quality audio interface and microphone that makes a direct digital connection to Apple's iPad (iPhone, iPod touch) and Mac. ONE features Apogee's Maestro control software, iOS device charging, optional battery power for portable recording with iPad and professional sound quality. ONE is the all-in-one solution that makes it easy for musicians, songwriters, recording engineers, film makers, audiophiles, and anyone else to enjoy professional sound quality on iPad and Mac.
ONE offers three input options; a built-in omni-directional condenser microphone, XLR input for dynamic, condenser or ribbon microphones, and 1/4" instrument input for electric guitars, keyboards or any instrument with an electric pick-up. An upgrade from the original design, ONE now has the ability to record two inputs simultaneously (instrument plus built-in microphone or external microphone). The updated AD/DA converters and mic preamps deliver best-in-class, studio quality sound and allow you to capture and playback your recordings with incredible clarity and detail.
ONE's audiophile quality headphone amplifier/DAC is a favorite for enhanced music listening on Mac. Now ONE delivers the same hi-fi quality sound to iPod touch, iPhone and iPad users for listening to streaming radio and music libraries with incredible clarity and detail.
ONE's built-in condenser microphone is a unique feature allowing anyone to record with incredible results and without the need for an external microphone. This paired with the option of connecting to iPod touch, iPhone or iPad and battery power enables studio-quality recordings to be created in any location.
"We have completely redesigned ONE, incorporating highly anticipated features; iPad compatibility, simultaneous recording of guitar and a microphone, enhanced sound quality, and a much desired metal chassis," says Apogee CEO and Co-Founder Betty Bennett. "This is an innovative interface, ideal for the musician who wants an all-in-one solution they can count on for ease of use and professional studio quality results, no matter where they are. We're excited to welcome this next generation of a classic Apogee product and we know our customers will love it."
Apple's iPad has revolutionized music creation with an intuitive touch interface and a universe of powerful and very affordable music apps. As a studio quality microphone and audio interface, ONE delivers key features to this new paradigm. Apogee's Maestro software for iOS lets you control ONE's inputs, mic preamp, outputs and set up low latency monitoring. ONE's DC power charges iPad while in use so recording is not interrupted. The option of battery power for ONE allows for truly portable professional recording.
When used with iPad or an iOS device, ONE works with any Core Audio compliant app like GarageBand, Auria and MultiTrack. For recording on a Mac, ONE works with Logic, Pro Tools, GarageBand, Ableton Live and any Mac Core Audio compliant application.
ONE for iPad and Mac - Highlights
First studio quality audio interface and microphone for iPad
New circuitry, mic capsule and upgraded sound quality
Redesigned die cast aluminum chassis
Direct digital connection to iPod touch, iPhone, iPad
Works with new iPhone 5, iPad (4th generation), iPad mini
(Lighting adapter required - Sold separately)
Works with GarageBand, MultiTrack, Spotify; Any Core Audio compatible app on iOS
Works with GarageBand, Logic, Pro Tools, Ableton, iTunes; Any Core Audio compatible app on Mac
Low latency monitoring, complete input/output control with Apogee's Maestro software (iOS & Mac)
DC power supplies charge to iPod touch, iPhone or iPad
Optional battery operation for remote recording on iPad (2 AA batteries not included)
USB 2.0 audio with 24-bit/96kHz A/D and D/A conversion
Built-in omnidirectional condenser microphone (mic stand adapter included)
2 Analog Inputs (XLR microphone and 1/4" instrument connector on breakout cable)
Record up to 2 inputs at a time (instrument + internal microphone or external microphone)
1 1/8" stereo output for headphones or powered speakers
Legendary Apogee sound quality
Designed in California - Made in the U.S.A.
System Requirements
Mac OS:
Computer: Intel Mac 1.5GHz or faster
Memory: 2 GB RAM minimum, 4 GB recommended
OS: 10.7.5 or greater
Connection and power: Any available USB port on a Mac
USB bus powered; DC power optional
(DC power supply included)
iOS:
iOS version: 5.1 and later
Connection: 30-pin dock connector
Power supply or two AA batteries required
(Batteries not included)
iOS device compatibility (Lightning connector)
iPod touch* (5th generation)
iPhone 5*
iPad* (4th generation)
iPad mini*
* Requires Apple's Lightning to 30-pin adapter. Sold separately.
iOS device compatibility (30-pin connector)
iPod touch (4th generation)
iPhone 4S
iPhone 4
iPad (3rd generation)
iPad 2
iPad
Price: $349
Availability: March 2013
Apogee Electronics introduces new Duet featuring iPad & Mac compatibility, MIDI I/O and new Maestro control app for iOS
Anaheim, California, January 24, 2013 - Apogee Electronics is pleased to introduce Duet for iPad and Mac, a 2 input, 4 output USB audio interface. The new Duet is the first professional stereo audio interface that makes a direct digital connection to Apple's iPad (iPhone, iPod touch) and Mac. Duet features Apogee's Maestro control software, iOS device charging, MIDI connectivity and professional sound quality. Duet is the ideal personal studio interface for stereo music recording, mixing and audiophile-quality listening on iPad and Mac.
First introduced in 2007, the original Duet was a 2 IN x 2 OUT FireWire Audio Interface for Mac and became one of the most popular audio interfaces of all time, starting a home studio revolution and winning many industry awards and accolades. Duet received an upgrade in May of 2011 when Duet 2 took its place with a new 2 IN x 4 OUT format, redesigned AD/DA conversion and mic preamps, and USB 2.0 Mac connectivity. The new Duet for iPad and Mac builds on this legacy by offering the same professional quality as the Duet 2 for the iPad based personal studio.
"Apogee has pioneered professional digital recording on iPad and iOS devices with products like JAM, our studio quality guitar input, and MiC, the first studio quality digital microphone for iPad and iPhone. We are now taking the next step, offering a range of professional multi-channel recording solutions for iPad and all iOS devices," says Apogee CEO and Co-Founder Betty Bennett. "Enabling amazing products like Duet to be directly connected to the increasingly powerful iPad and all other iOS devices, seamlessly integrated with apps like GarageBand and Auria, controlled with our Maestro software allows you take mobile music creation to the next level. It truly is a new frontier for the personal studio and we're proud to be at the forefront."
Apple's iPad has revolutionized music creation with an intuitive touch interface and a universe of powerful and very affordable music apps. Duet delivers key features to this new paradigm that bring professional stereo audio recording to iPad for the first time. Apogee's Maestro software for iOS lets you control Duet's inputs, mic preamps, outputs and set up low latency monitoring. Duet's DC power charges iPad while in use so recording is not interrupted. Duet provides plenty of power for studio headphones, microphones and MIDI keyboards. In addition, Duet accepts and provides professional audio level (ie. balanced, +4 dBu reference level).
When used with iPad or an iOS device, Duet works with any Core Audio compliant app like GarageBand, Auria and MultiTrack. For recording on a Mac, Duet works with Logic, Pro Tools, GarageBand, Ableton Live and any Mac Core Audio compliant application.
Duet for iPad and Mac - Highlights
First professional stereo audio interface for iPad
Direct digital connection to iPod touch, iPhone, iPad
Works with new iPhone 5, iPad (4th generation), iPad mini
(Apple's Lighting to 30-pin adapter required - Sold separately)
Works with GarageBand, Auria, MultiTrack; Any Core Audio compatible app on iOS
Works with GarageBand, Logic, Pro Tools, Ableton; Any Core Audio compatible app on Mac
Low latency monitoring, complete input/output control with Apogee's Maestro software (iOS & Mac)
MIDI input/output (USB-A type connector)
DC power supplies charge to iPod touch, iPhone or iPad
USB 2.0 audio with 24-bit/192kHz A/D and D/A conversion
2 Analog inputs with world-class mic preamps and selectable 48v phantom power
2 Balanced analog line outputs
1 Independent 1/4" stereo headphone output
Legendary Apogee sound quality
Designed in California - Made in the U.S.A.
System Requirements
Mac OS:
Computer: Intel Mac 1.5GHz or faster
Memory: 2 GB RAM minimum, 4 GB recommended
OS: 10.6.8, 10.7.4 or greater
Connection and power: Any available USB port on a Mac
USB bus powered; DC power optional
(DC power supply included)
iOS:
iOS version: 5.1 and later
Connection: 30-pin dock connector
DC Power supply included
iOS device compatibility (Lightning connector)
iPod touch* (5th generation)
iPhone 5*
iPad* (4th generation)
iPad mini*
* Requires Apple's Lightning to 30-pin adapter. Sold separately.
iOS device compatibility (30-pin connector)
iPod touch (4th generation)
iPhone 4S
iPhone 4
iPad (3rd generation)
iPad 2
iPad
Price: $595
Availability: February 2013
Apogee Electronics announces iPad compatibility for Quartet USB audio interface and new Maestro control app for iOS
Anaheim, California, January 24, 2013 - Apogee Electronics is pleased to announce iPad compatibility for Quartet, a 4 input, 8 output USB audio interface. Quartet is the first professional multi-channel audio interface that makes a direct digital connection to Apple's iPad (iPhone, iPod touch) and Mac. Quartet for iPad and Mac features Apogee's Maestro control software, iOS device charging, MIDI connectivity, advanced monitor control and professional sound quality. Quartet is the ideal studio control center for multi-channel music recording and mixing on iPad and Mac.
"Apogee has pioneered professional digital recording on iPad and iOS devices with products like JAM, our studio quality guitar input, and MiC, the first studio quality digital microphone for iPad & iOS. We are now taking the next step, offering a range of professional multi-channel recording solutions for iPad and all iOS devices," says Apogee CEO and Co-Founder Betty Bennett.
"Enabling amazing products like Quartet to be directly connected to the increasingly powerful iPad and all other iOS devices, seamlessly integrated with apps like GarageBand and Auria, controlled with our Maestro software allows you take mobile music creation to the next level. It truly is a new frontier for the personal studio and we're proud to be at the forefront."
Apple's iPad has revolutionized music creation with an intuitive touch interface and a universe of powerful and very affordable music apps. Quartet delivers key features to this new paradigm that bring professional multi-channel audio recording to iPad for the first time. Apogee's Maestro software for iOS lets you control Quartet's inputs, mic preamps, outputs and set up low latency monitoring. Quartet's DC power charges iPad while in use so recording is not interrupted. Quartet provides plenty of power for studio headphones, microphones and MIDI keyboards. In addition, Quartet accepts and provides professional audio level (ie. balanced, +4 dBu reference level).
When used with iPad or an iOS device, Quartet works with any Core Audio compliant app like GarageBand, Auria and MultiTrack. For recording on a Mac, Quartet works with Logic, Pro Tools, GarageBand, Ableton Live and any Mac Core Audio compliant application.
Quartet for iPad and Mac - Highlights
First professional multi-channel audio interface for iPad
Direct digital connection to iPod touch, iPhone, iPad
Works with new iPhone 5, iPad (4th generation), iPad mini
(Apple's Lighting to 30-pin adapter required - Sold separately)
Works with GarageBand, Auria, MultiTrack and any Core Audio compliant app on iOS
Works with GarageBand, Logic, Pro Tools, Ableton and any Core Audio compliant app on Mac
Low latency monitoring, complete input/output control with Apogee's Maestro software (iOS & Mac)
MIDI input/output (USB-A type connector)
DC power supplies charge to iPod touch, iPhone or iPad
USB 2.0 audio with 24-bit/192kHz A/D and D/A conversion
4 Analog inputs with world-class mic preamps and selectable 48v phantom power
6 Balanced analog line outputs
ADAT/SMUX digital Inputs
Monitor control - up to 3 speaker sets
1 Independent 1/4" stereo headphone output
QuickTouch pads for input/output selection and advanced control
Legendary Apogee sound quality
Designed in California - Made in the U.S.A.
System Requirements
Mac OS:
Computer: Intel Mac 1.5GHz or faster
Memory: 2 GB RAM minimum, 4 GB recommended
OS: 10.6.8, 10.7.4 or greater
Connection and power: Any available USB port on a Mac
Power: DC Power supply included
iOS:
iOS version: 5.1 and later
Connection: 30-pin dock connector
DC Power supply included
iOS device compatibility (Lightning connector)
iPod touch* (5th generation)
iPhone 5*
iPad* (4th generation)
iPad mini*
* Requires Apple's Lightning to 30-pin adapter. Sold separately.
iOS device compatibility (30-pin connector)
iPod touch (4th generation)
iPhone 4S
iPhone 4
iPad (3rd generation)
iPad 2
iPad
Price: $1295
Availability: February 2013
Filed under: Home Entertainment, Peripherals, Portable Audio/Video, Apple
Source: Apogee (1), (2), (3)
Source: http://www.engadget.com/2013/01/24/apogee-intros-revamped-one-duet-and-quartet-audio-interfaces/
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